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Snai1-induced partial epithelial–mesenchymal transition orchestrates p53–p21-mediated G2/M arrest in the progression of renal fibrosis via NF-κB-mediated inflammation
Renal fibrosis is the common feature of all progressive kidney diseases and exerts great burden on public health worldwide. The maladaptive repair mechanism of tubular epithelial cells, an important mediator of renal fibrogenesis, manifests with partial epithelial–mesenchymal transition (EMT) and ce...
Autores principales: | Qi, Ruochen, Wang, Jiyan, Jiang, Yamei, Qiu, Yue, Xu, Ming, Rong, Ruiming, Zhu, Tongyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790819/ https://www.ncbi.nlm.nih.gov/pubmed/33414422 http://dx.doi.org/10.1038/s41419-020-03322-y |
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