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NF-κB activity during pancreas development regulates adult β-cell mass by modulating neonatal β-cell proliferation and apoptosis

NF-κB is a well-characterized transcription factor, widely known for its roles in inflammation and immune responses, as well as in control of cell division and apoptosis. However, its function in β-cells is still being debated, as it appears to depend on the timing and kinetics of its activation. To...

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Detalles Bibliográficos
Autores principales: Sever, Dror, Hershko-Moshe, Anat, Srivastava, Rohit, Eldor, Roy, Hibsher, Daniel, Keren-Shaul, Hadas, Amit, Ido, Bertuzzi, Federico, Krogvold, Lars, Dahl-Jørgensen, Knut, Ben-Dov, Iddo Z., Landsman, Limor, Melloul, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790827/
https://www.ncbi.nlm.nih.gov/pubmed/33414444
http://dx.doi.org/10.1038/s41420-020-00386-9