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FAT10 protects against ischemia-induced ventricular arrhythmia by decreasing Nedd4-2/Nav1.5 complex formation

The human leukocyte antigen F-associated transcript 10 (FAT10) is a member of the small ubiquitin-like protein family that binds to its target proteins and subjects them to degradation by the ubiquitin–proteasome system (UPS). In the heart, FAT10 plays a cardioprotective role and affects predisposit...

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Detalles Bibliográficos
Autores principales: Liu, Xiao, Ge, Jin, Chen, Chen, Shen, Yang, Xie, Jinyan, Zhu, Xin, Liu, Menglu, Hu, Jinzhu, Chen, Leifeng, Guo, Linjuan, Zhou, Qiongqiong, Yan, Xia, Qiu, Yuming, Wan, Rong, Marian, Ali J., Hong, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790828/
https://www.ncbi.nlm.nih.gov/pubmed/33414395
http://dx.doi.org/10.1038/s41419-020-03290-3