CRISPR-Cas9-Edited Tacrolimus-Resistant Antiviral T Cells for Advanced Adoptive Immunotherapy in Transplant Recipients

Viral infections, such as with cytomegalovirus (CMV), remain a major risk factor for mortality and morbidity of transplant recipients because of their requirement for lifelong immunosuppression (IS). Antiviral drugs often cause toxicity and sometimes fail to control disease. Thus, regeneration of th...

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Detalles Bibliográficos
Autores principales: Amini, Leila, Wagner, Dimitrios Laurin, Rössler, Uta, Zarrinrad, Ghazaleh, Wagner, Livia Felicitas, Vollmer, Tino, Wendering, Désirée Jacqueline, Kornak, Uwe, Volk, Hans-Dieter, Reinke, Petra, Schmueck-Henneresse, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791012/
https://www.ncbi.nlm.nih.gov/pubmed/32956624
http://dx.doi.org/10.1016/j.ymthe.2020.09.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791012/
https://www.ncbi.nlm.nih.gov/pubmed/32956624
http://dx.doi.org/10.1016/j.ymthe.2020.09.011

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