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CRISPR-Cas9-Edited Tacrolimus-Resistant Antiviral T Cells for Advanced Adoptive Immunotherapy in Transplant Recipients
Viral infections, such as with cytomegalovirus (CMV), remain a major risk factor for mortality and morbidity of transplant recipients because of their requirement for lifelong immunosuppression (IS). Antiviral drugs often cause toxicity and sometimes fail to control disease. Thus, regeneration of th...
Autores principales: | Amini, Leila, Wagner, Dimitrios Laurin, Rössler, Uta, Zarrinrad, Ghazaleh, Wagner, Livia Felicitas, Vollmer, Tino, Wendering, Désirée Jacqueline, Kornak, Uwe, Volk, Hans-Dieter, Reinke, Petra, Schmueck-Henneresse, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791012/ https://www.ncbi.nlm.nih.gov/pubmed/32956624 http://dx.doi.org/10.1016/j.ymthe.2020.09.011 |
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