PLPP/CIN-mediated NF2-serine 10 dephosphorylation regulates F-actin stability and Mdm2 degradation in an activity-dependent manner

Neurofibromin 2 (NF2, also known as merlin) is a tumor suppressor protein encoded by the neurofibromatosis type 2 gene NF2. NF2 is also an actin-binding protein that functions in an intrinsic signaling network critical for actin dynamics. Although protein kinase A (PKA)-mediated NF2-serin (S) 10 pho...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Eun, Lee, Duk-Shin, Kim, Tae-Hyun, Park, Hana, Kim, Min-Ju, Kang, Tae-Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791067/
https://www.ncbi.nlm.nih.gov/pubmed/33414453
http://dx.doi.org/10.1038/s41419-020-03325-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791067/
https://www.ncbi.nlm.nih.gov/pubmed/33414453
http://dx.doi.org/10.1038/s41419-020-03325-9

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