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Combined and selective miR-21 silencing and doxorubicin delivery in cancer cells using tailored DNA nanostructures

MicroRNAs play an important role in tumorigenesis and, among them, miR-21 is found to be aberrantly up-regulated in various tumors. The tumor-associated antigen, folate receptor alpha is a GPI-membrane protein overexpressed in many malignant tumors of epithelial origin, including ovarian and cervica...

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Detalles Bibliográficos
Autores principales: Raniolo, Sofia, Unida, Valeria, Vindigni, Giulia, Stolfi, Carmine, Iacovelli, Federico, Desideri, Alessandro, Biocca, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791072/
https://www.ncbi.nlm.nih.gov/pubmed/33414439
http://dx.doi.org/10.1038/s41419-020-03339-3