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Combined and selective miR-21 silencing and doxorubicin delivery in cancer cells using tailored DNA nanostructures
MicroRNAs play an important role in tumorigenesis and, among them, miR-21 is found to be aberrantly up-regulated in various tumors. The tumor-associated antigen, folate receptor alpha is a GPI-membrane protein overexpressed in many malignant tumors of epithelial origin, including ovarian and cervica...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791072/ https://www.ncbi.nlm.nih.gov/pubmed/33414439 http://dx.doi.org/10.1038/s41419-020-03339-3 |