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MicroRNA-93/STAT3 signalling pathway mediates retinal microglial activation and protects retinal ganglion cells in an acute ocular hypertension model

Glaucoma is a common neurodegenerative disease and a leading cause of irreversible blindness worldwide. Retinal microglia-mediated neuroinflammation is involved in the process of optic nerve damage, but the mechanisms driving this microglial activation remain mostly elusive. Previous investigations...

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Detalles Bibliográficos
Autores principales: Wang, Yayi, Chen, Shida, Wang, Jiawei, Liu, Yaoming, Chen, Yang, Wen, Tao, Fang, Xiuli, Vidal-Sanz, Manuel, Jonas, Jost B., Zhang, Xiulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791106/
https://www.ncbi.nlm.nih.gov/pubmed/33414426
http://dx.doi.org/10.1038/s41419-020-03337-5