Cargando…

MicroRNA-93/STAT3 signalling pathway mediates retinal microglial activation and protects retinal ganglion cells in an acute ocular hypertension model

Glaucoma is a common neurodegenerative disease and a leading cause of irreversible blindness worldwide. Retinal microglia-mediated neuroinflammation is involved in the process of optic nerve damage, but the mechanisms driving this microglial activation remain mostly elusive. Previous investigations...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yayi, Chen, Shida, Wang, Jiawei, Liu, Yaoming, Chen, Yang, Wen, Tao, Fang, Xiuli, Vidal-Sanz, Manuel, Jonas, Jost B., Zhang, Xiulan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791106/ https://www.ncbi.nlm.nih.gov/pubmed/33414426 http://dx.doi.org/10.1038/s41419-020-03337-5

Ejemplares similares

Microglial dynamics after axotomy-induced retinal ganglion cell death
por: Nadal-Nicolás, Francisco M., et al.
Publicado: (2017)

MicroRNA regulation in an animal model of acute ocular hypertension
por: Wang, Jiawei, et al.
Publicado: (2016)

Transcorneal Electrical Stimulation Inhibits Retinal Microglial Activation and Enhances Retinal Ganglion Cell Survival After Acute Ocular Hypertensive Injury
por: Fu, Lin, et al.
Publicado: (2018)

Retinal Ganglion Cell Loss and Microglial Activation in a SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis
por: Rojas, Pilar, et al.
Publicado: (2021)

Retinal ganglion cell axonal compression by retinal vessels in light-induced retinal degeneration
por: García-Ayuso, Diego, et al.
Publicado: (2011)

Retinal remodeling following photoreceptor degeneration causes retinal ganglion cell death
por: García-Ayuso, Diego, et al.
Publicado: (2018)

Mouse model of ocular hypertension with retinal ganglion cell degeneration
por: Mukai, Ryo, et al.
Publicado: (2019)

Ocular direct current stimulation affects retinal ganglion cells
por: Blum, Maren-Christina, et al.
Publicado: (2021)

Inflammatory cytokine profiles in eyes with primary angle-closure glaucoma
por: Wang, Yayi, et al.
Publicado: (2018)

Caveolin-1 Protects Retinal Ganglion Cells against Acute Ocular Hypertension Injury via Modulating Microglial Phenotypes and Distribution and Activating AKT pathway
por: Zhang, Liwei, et al.
Publicado: (2017)

Selective vulnerability of the intermediate retinal capillary plexus precedes retinal ganglion cell loss in ocular hypertension
por: Pitale, Priyamvada M., et al.
Publicado: (2022)

Activation of adenosine A(3) receptor protects retinal ganglion cells from degeneration induced by ocular hypertension
por: Boia, Raquel, et al.
Publicado: (2020)

JUN is important for ocular hypertension-induced retinal ganglion cell degeneration
por: Syc-Mazurek, Stephanie B, et al.
Publicado: (2017)

Caffeine administration prevents retinal neuroinflammation and loss of retinal ganglion cells in an animal model of glaucoma
por: Madeira, Maria H., et al.
Publicado: (2016)

Role of Oxidative Stress in Ocular Diseases Associated with Retinal Ganglion Cells Degeneration
por: Kang, Eugene Yu-Chuan, et al.
Publicado: (2021)

Displaced retinal ganglion cells in albino and pigmented rats
por: Nadal-Nicolás, Francisco M., et al.
Publicado: (2014)

Keratin8 Deficiency Aggravates Retinal Ganglion Cell Damage Under Acute Ocular Hypertension
por: Zhang, Chengshou, et al.
Publicado: (2023)

P2X7 receptor antagonist protects retinal ganglion cells by inhibiting microglial activation in a rat chronic ocular hypertension model
por: Dong, Lingdan, et al.
Publicado: (2018)

Protection of Retinal Ganglion Cells and Retinal Vasculature by Lycium Barbarum Polysaccharides in a Mouse Model of Acute Ocular Hypertension
por: Mi, Xue-Song, et al.
Publicado: (2012)

The retina of the lab rat: focus on retinal ganglion cells and photoreceptors
por: Galindo-Romero, Caridad, et al.
Publicado: (2022)

Retinal Ganglion Cell Death as a Late Remodeling Effect of Photoreceptor Degeneration
por: García-Ayuso, Diego, et al.
Publicado: (2019)

Panton–Valentine Leukocidin Colocalizes with Retinal Ganglion and Amacrine Cells and Activates Glial Reactions and Microglial Apoptosis
por: Liu, XuanLi, et al.
Publicado: (2018)

Pan-retinal ganglion cell markers in mice, rats, and rhesus macaques
por: Nadal-Nicolás, Francisco M., et al.
Publicado: (2023)

Ocular Hypertension Drives Remodeling of AMPA Receptors in Select Populations of Retinal Ganglion Cells
por: Sladek, Asia L., et al.
Publicado: (2020)

Protection of the Retinal Ganglion Cells: Intravitreal Injection of Resveratrol in Mouse Model of Ocular Hypertension
por: Cao, Kejia, et al.
Publicado: (2020)

Phototransduction in Retinal Ganglion Cells
por: Detwiler, Peter B.
Publicado: (2018)

Melanopsin expression is an indicator of the well-being of melanopsin-expressing retinal ganglion cells but not of their viability
por: Agudo-Barriuso, Marta, et al.
Publicado: (2016)

Alpha retinal ganglion cells in pigmented mice retina: number and distribution
por: Gallego-Ortega, Alejandro, et al.
Publicado: (2022)

Photosensitive Melanopsin-Containing Retinal Ganglion Cells in Health and Disease: Implications for Circadian Rhythms
por: Lax, Pedro, et al.
Publicado: (2019)

Coordinated Intervention of Microglial and Müller Cells in Light-Induced Retinal Degeneration
por: Di Pierdomenico, Johnny, et al.
Publicado: (2020)

Retinal microglial activation in glaucoma: evolution over time in a unilateral ocular hypertension model
por: Fernández-Albarral, José A., et al.
Publicado: (2021)

Retinal Ganglion Cells are Resistant to Photoreceptor Loss in Retinal Degeneration
por: Lin, Bin, et al.
Publicado: (2013)

Bifidobacterium promotes retinal ganglion cell survival by regulating the balance of retinal glial cells
por: Zhao, Xiaohuan, et al.
Publicado: (2023)

Generation of self-organized sensory ganglion organoids and retinal ganglion cells from fibroblasts
por: Xiao, Dongchang, et al.
Publicado: (2020)

MiR-93-5p inhibits retinal neurons apoptosis by regulating PDCD4 in acute ocular hypertension model
por: Tan, Cheng, et al.
Publicado: (2023)

Ocular Biometry in Primary Angle-Closure Glaucoma Associated with Retinitis Pigmentosa
por: Xu, Jiangang, et al.
Publicado: (2017)

Commentary: Retinal Waves Modulate an Intraretinal Circuit of Intrinsically Photosensitive Retinal Ganglion Cells
por: Chen, Yu-Chieh D.
Publicado: (2018)

Modulation of microglia by Wolfberry on the survival of retinal ganglion cells in a rat ocular hypertension model
por: Chiu, Kin, et al.
Publicado: (2009)

Modulation of microglia by Wolfberry on the survival of retinal ganglion cells in a rat ocular hypertension model
por: Chiu, Kin, et al.
Publicado: (2009)

The Nrf2 Signaling in Retinal Ganglion Cells under Oxidative Stress in Ocular Neurodegenerative Diseases
por: Liu, Xiu-Fen, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_u9r9cgtbvdl3je6gtit8mgbs72