TRIB2 modulates proteasome function to reduce ubiquitin stability and protect liver cancer cells against oxidative stress

The regulation of homeostasis in the Ubiquitin (Ub) proteasome system (UPS) is likely to be important for the development of liver cancer. Tribbles homolog 2 (TRIB2) is known to affect Ub E3 ligases (E3s) in liver cancer. However, whether TRIB2 regulates the UPS in other ways and the relevant mechan...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Susu, Chen, Yuxin, Yang, Yueyue, Zhang, Xiao, Ma, Lifang, Xue, Xiangfei, Qiao, Yongxia, Wang, Jiayi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791120/
https://www.ncbi.nlm.nih.gov/pubmed/33414446
http://dx.doi.org/10.1038/s41419-020-03299-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791120/
https://www.ncbi.nlm.nih.gov/pubmed/33414446
http://dx.doi.org/10.1038/s41419-020-03299-8

Ejemplares similares