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HOXA5 counteracts the function of pathological scar-derived fibroblasts by partially activating p53 signaling

The inactivation of p53 can lead to the formation of pathological scars, including hypertrophic scars and keloids. HOXA5 has been reported to be a critical transcription factor in the p53 pathway in cancers. However, whether HOXA5 also plays a role in pathological scar progression through activating...

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Detalles Bibliográficos
Autores principales: Liang, Yimin, Zhou, Renpeng, Fu, Xiujun, Wang, Chen, Wang, Danru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791133/
https://www.ncbi.nlm.nih.gov/pubmed/33414417
http://dx.doi.org/10.1038/s41419-020-03323-x