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FGF9 promotes mouse spermatogonial stem cell proliferation mediated by p38 MAPK signalling

OBJECTIVES: Fibroblast growth factor 9 (FGF9) is expressed by somatic cells in the seminiferous tubules, yet little information exists about its role in regulating spermatogonial stem cells (SSCs). MATERIALS AND METHODS: Fgf9 overexpression lentivirus was injected into mouse testes, and PLZF immunos...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Whelan, Eoin C., Guan, Xuebing, Deng, Bingquan, Wang, Shu, Sun, Jiachen, Avarbock, Mary R., Wu, Xin, Brinster, Ralph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791179/
https://www.ncbi.nlm.nih.gov/pubmed/33107118
http://dx.doi.org/10.1111/cpr.12933