Acid‐sensing ion channels regulate nucleus pulposus cell inflammation and pyroptosis via the NLRP3 inflammasome in intervertebral disc degeneration

OBJECTIVE: Lactate accumulation is an important factor in the intervertebral disc degeneration (IVDD). Currently, the effect and underlying mechanism of action of lactate on nucleus pulposus (NP) cell inflammation during IVDD are unclear. Previous studies have found that the NLRP3 inflammasome plays...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Kangcheng, An, Ran, Xiang, Qian, Li, Gaocai, Wang, Kun, Song, Yu, Liao, Zhiwei, Li, Shuai, Hua, Wenbin, Feng, Xiaobo, Wu, Xinghuo, Zhang, Yukun, Das, Abhirup, Yang, Cao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791185/
https://www.ncbi.nlm.nih.gov/pubmed/33111436
http://dx.doi.org/10.1111/cpr.12941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791185/
https://www.ncbi.nlm.nih.gov/pubmed/33111436
http://dx.doi.org/10.1111/cpr.12941

Ejemplares similares