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T cell co-stimulator inducible co-stimulatory (ICOS) exerts potential anti-atherosclerotic roles through downregulation of vascular smooth muscle phagocytosis and proliferation

BACKGROUND: Atherosclerosis (AS) is a chronic inflammatory disease. The role of the immune system in the etiology of the disease, particularly T cells, has been widely studied and is well established. T cell activation directly regulates co-signaling molecules present in immune synapses. Targeting o...

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Detalles Bibliográficos
Autores principales: Zhong, Zhixiong, Zhang, Qunji, Tan, Linkai, Guo, Xuemin, Gan, Caiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791234/
https://www.ncbi.nlm.nih.gov/pubmed/33437796
http://dx.doi.org/10.21037/atm-20-7342