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The rocaglate CR-31-B (−) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of COVID-19, a severe respiratory disease with varying clinical presentations and outcomes, and responsible for a major pandemic that started in early 2020. With no vaccines or effective antiviral treatments availabl...

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Detalles Bibliográficos
Autores principales: Müller, Christin, Obermann, Wiebke, Karl, Nadja, Wendel, Hans-Guido, Taroncher-Oldenburg, Gaspar, Pleschka, Stephan, Hartmann, Roland K., Grünweller, Arnold, Ziebuhr, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791309/
https://www.ncbi.nlm.nih.gov/pubmed/33422611
http://dx.doi.org/10.1016/j.antiviral.2021.105012