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The UVSSA complex alleviates MYC-driven transcription stress

Cancer cells develop strong genetic dependencies, enabling survival under oncogenic stress. MYC is a key oncogene activated across most cancers, and identifying associated synthetic lethality or sickness can provide important clues about its activity and potential therapeutic strategies. On the basi...

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Detalles Bibliográficos
Autores principales: Sato, Mai, Liebau, Rowyn C., Liu, Zhaoqi, Liu, Lizhi, Rabadan, Raul, Gautier, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791342/
https://www.ncbi.nlm.nih.gov/pubmed/33404608
http://dx.doi.org/10.1083/jcb.201807163