DNA damage promotes microtubule dynamics through a DNA-PK-AKT axis for enhanced repair

DNA double-strand breaks (DSBs) are mainly repaired by c-NHEJ and HR pathways. The enhanced DSB mobility after DNA damage is critical for efficient DSB repair. Although microtubule dynamics have been shown to regulate DSB mobility, the reverse effect of DSBs to microtubule dynamics remains elusive....

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Detalles Bibliográficos
Autores principales: Ma, Shuyun, Rong, Zeming, Liu, Chen, Qin, Xiaobing, Zhang, Xiaoyan, Chen, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791344/
https://www.ncbi.nlm.nih.gov/pubmed/33404607
http://dx.doi.org/10.1083/jcb.201911025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791344/
https://www.ncbi.nlm.nih.gov/pubmed/33404607
http://dx.doi.org/10.1083/jcb.201911025

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