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Delaying the final cut: A close encounter of checkpoint kinases at the midbody

How chromatin bridges are relayed to the chromosomal passenger complex (CPC) during mammalian cell division is unknown. In this issue, Petsalaki and Zachos (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202008029) show that the DNA damage checkpoint kinases ATM and Chk2 signal to the CPC to associ...

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Detalles Bibliográficos
Autores principales: Hadders, Michael A., Lens, Susanne M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791345/
https://www.ncbi.nlm.nih.gov/pubmed/33404606
http://dx.doi.org/10.1083/jcb.202012130