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Intramuscular injection of Botox causes tendon atrophy by induction of senescence of tendon-derived stem cells

BACKGROUND: Botulinum toxin (Botox) injection is in widespread clinical use for the treatment of muscle spasms and tendinopathy but the mechanism of action is poorly understood. HYPOTHESIS: We hypothesised that the reduction of patellar-tendon mechanical-loading following intra-muscular injection of...

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Detalles Bibliográficos
Autores principales: Chen, Peilin, Chen, Ziming, Mitchell, Christopher, Gao, Junjie, Chen, Lianzhi, Wang, Allan, Leys, Toby, Landao-Bassonga, Euphemie, Zheng, Qiujian, Wang, Tao, Zheng, Minghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791643/
https://www.ncbi.nlm.nih.gov/pubmed/33413592
http://dx.doi.org/10.1186/s13287-020-02084-w