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The therapeutic efficacy of mesenchymal stromal cells on experimental colitis was improved by the IFN-γ and poly(I:C) priming through promoting the expression of indoleamine 2,3-dioxygenase

BACKGROUND: Inflammatory bowel disease is a chronic and excessive inflammation of the colon and small intestine. We previously reported that priming of mesenchymal stromal cells (MSCs) with poly(I:C) induced them to express indoleamine 2,3-dioxygenase (IDO). We tried to find out whether the IFN-γ an...

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Detalles Bibliográficos
Autores principales: Lim, Ji-Young, Kim, Byung-Su, Ryu, Da-Bin, Kim, Tae Woo, Park, Gyeongsin, Min, Chang-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791665/
https://www.ncbi.nlm.nih.gov/pubmed/33413597
http://dx.doi.org/10.1186/s13287-020-02087-7