microRNA-27b shuttled by mesenchymal stem cell-derived exosomes prevents sepsis by targeting JMJD3 and downregulating NF-κB signaling pathway

BACKGROUND: Exosomal microRNAs (miRs) derived from mesenchymal stem cells (MSCs) have been shown to play roles in the pathophysiological processes of sepsis. Moreover, miR-27b is highly enriched in MSC-derived exosomes. Herein, we aimed to investigate the potential role and downstream molecular mech...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Jia, Sun, Xuan, Chen, Junhui, Liao, Xin, He, Yixuan, Wang, Jinsong, Chen, Rui, Hu, Sean, Qiu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791667/
https://www.ncbi.nlm.nih.gov/pubmed/33413595
http://dx.doi.org/10.1186/s13287-020-02068-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791667/
https://www.ncbi.nlm.nih.gov/pubmed/33413595
http://dx.doi.org/10.1186/s13287-020-02068-w

Ejemplares similares