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microRNA-27b shuttled by mesenchymal stem cell-derived exosomes prevents sepsis by targeting JMJD3 and downregulating NF-κB signaling pathway

BACKGROUND: Exosomal microRNAs (miRs) derived from mesenchymal stem cells (MSCs) have been shown to play roles in the pathophysiological processes of sepsis. Moreover, miR-27b is highly enriched in MSC-derived exosomes. Herein, we aimed to investigate the potential role and downstream molecular mech...

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Detalles Bibliográficos
Autores principales:	Sun, Jia, Sun, Xuan, Chen, Junhui, Liao, Xin, He, Yixuan, Wang, Jinsong, Chen, Rui, Hu, Sean, Qiu, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791667/ https://www.ncbi.nlm.nih.gov/pubmed/33413595 http://dx.doi.org/10.1186/s13287-020-02068-w

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