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Sex- and age‐dependent alterations of splenic immune cell profile and NK cell phenotypes and function in C57BL/6J mice

BACKGROUND: Physiological homeostasis decline, immunosenescence, and increased risk for multiple diseases, including neurodegeneration, are all hallmarks of ageing. Importantly, it is known that the ageing process is sex-biased. For example, there are sex differences in predisposition for multiple a...

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Detalles Bibliográficos
Autores principales: Menees, Kelly B., Earls, Rachael H., Chung, Jaegwon, Jernigan, Janna, Filipov, Nikolay M., Carpenter, Jessica M., Lee, Jae-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791703/
https://www.ncbi.nlm.nih.gov/pubmed/33419446
http://dx.doi.org/10.1186/s12979-021-00214-3