Cargando…

Quantitative profiling of N(6)-methyladenosine at single-base resolution in stem-differentiating xylem of Populus trichocarpa using Nanopore direct RNA sequencing

There are no comprehensive methods to identify N(6)-methyladenosine (m(6)A) at single-base resolution for every single transcript, which is necessary for the estimation of m(6)A abundance. We develop a new pipeline called Nanom6A for the identification and quantification of m(6)A modification at sin...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Yubang, Liu, Xuqing, Wu, Bizhi, Wang, Huihui, Xi, Feihu, Kohnen, Markus V., Reddy, Anireddy S. N., Gu, Lianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791831/
https://www.ncbi.nlm.nih.gov/pubmed/33413586
http://dx.doi.org/10.1186/s13059-020-02241-7