FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer progression and metastasis

BACKGROUND: Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that is overexpressed or activated in several advanced-stage solid cancers. It is known to play both kinase-dependent and -independent roles in promoting tumor progression and metastasis. Numerous inhibitors, targeting either...

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Detalles Bibliográficos
Autores principales: Antoniades, Ioanna, Kyriakou, Maria, Charalambous, Anna, Kalalidou, Katerina, Christodoulou, Andri, Christoforou, Maria, Skourides, Paris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791867/
https://www.ncbi.nlm.nih.gov/pubmed/33413438
http://dx.doi.org/10.1186/s12964-020-00671-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791867/
https://www.ncbi.nlm.nih.gov/pubmed/33413438
http://dx.doi.org/10.1186/s12964-020-00671-1

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