NAMPT/SIRT1 Attenuate Ang II-Induced Vascular Remodeling and Vulnerability to Hypertension by Inhibiting the ROS/MAPK Pathway

Hypertension is characterized by endothelial dysfunction, vascular remodeling, and rearrangement of the extracellular matrix. Besides, the pathogenesis of hypertension is closely related to excess generation of reactive oxygen species (ROS). Nicotinamide phosphoribosyltransferase (NAMPT) is a rate-l...

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Detalles Bibliográficos
Autores principales: Zhou, Lei, Zhang, Sheng, Bolor-Erdene, Enkhbat, Wang, Lingwei, Tian, Ding, Mei, Yunqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791967/
https://www.ncbi.nlm.nih.gov/pubmed/33488923
http://dx.doi.org/10.1155/2020/1974265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791967/
https://www.ncbi.nlm.nih.gov/pubmed/33488923
http://dx.doi.org/10.1155/2020/1974265

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