Metapristone (RU486-derivative) inhibits endometrial cancer cell progress through regulating miR-492/Klf5/Nrf1 axis

BACKGROUND: Endometrial cancer is an invasive gynecological cancer prevalent in the world. The pathogenesis of endometrial cancer is related to multiple levels of regulation, referring to oestrogen, tumor-suppressor gene (e.g. PTEN) or microRNAs (e.g. miR-23a and miR-29b). Metapristone is a hormone-...

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Detalles Bibliográficos
Autores principales: Chang, Yue, Hao, Min, Jia, Ru, Zhao, Yihui, Cai, Yixuan, Liu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792070/
https://www.ncbi.nlm.nih.gov/pubmed/33413440
http://dx.doi.org/10.1186/s12935-020-01682-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792070/
https://www.ncbi.nlm.nih.gov/pubmed/33413440
http://dx.doi.org/10.1186/s12935-020-01682-1

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