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Metapristone (RU486-derivative) inhibits endometrial cancer cell progress through regulating miR-492/Klf5/Nrf1 axis
BACKGROUND: Endometrial cancer is an invasive gynecological cancer prevalent in the world. The pathogenesis of endometrial cancer is related to multiple levels of regulation, referring to oestrogen, tumor-suppressor gene (e.g. PTEN) or microRNAs (e.g. miR-23a and miR-29b). Metapristone is a hormone-...
Autores principales: | Chang, Yue, Hao, Min, Jia, Ru, Zhao, Yihui, Cai, Yixuan, Liu, Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792070/ https://www.ncbi.nlm.nih.gov/pubmed/33413440 http://dx.doi.org/10.1186/s12935-020-01682-1 |
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