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Mesenchymal stem cells desensitize castration-resistant prostate cancer to docetaxel chemotherapy via inducing TGF-β1-mediated cell autophagy

BACKGROUND: Mesenchymal stem cells (MSCs) have been proved to drive castration resistant prostate cancer (CRPC). In this study, we aim to investigate the contribution of MSCs to the development of docetaxel resistance in CRPC cells and its potential mechanisms. METHODS: The effect of MSCs on CRPC ce...

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Detalles Bibliográficos
Autores principales: Yu, Yang, Yang, Fu-han, Zhang, Wen-tao, Guo, Ya-dong, Ye, Lin, Yao, Xu-dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792182/
https://www.ncbi.nlm.nih.gov/pubmed/33413648
http://dx.doi.org/10.1186/s13578-020-00494-0