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BIRC3 and BIRC5: multi‐faceted inhibitors in cancer

BACKGROUND: The evasion from apoptosis is a common strategy adopted by most tumors, and inhibitors of apoptosis proteins (IAPs) are among the most studied molecular and therapeutic targets. BIRC3 (cellular IAP2) and BIRC5 (survivin) are two of the eight members of the human IAPs family. This family...

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Detalles Bibliográficos
Autor principal: Frazzi, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792207/
https://www.ncbi.nlm.nih.gov/pubmed/33413657
http://dx.doi.org/10.1186/s13578-020-00521-0