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Short tandem repeat near hypoxia response element (HRE) instead of HRE genetic variants in promoter calcitonin receptor-like receptor (CRLR) gene as risk factor in severe preeclampsia: a preliminary study

OBJECTIVE: Calcitonin receptor-like receptor (CRLR) regulates vasoconstriction and dilatation; the expression increases during hypoxia via activation of hypoxia response element (HRE) in CRLR gene promoter region. Variant in HRE, as well short tandem repeat (STR) variants near HRE in CRLR alters the...

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Detalles Bibliográficos
Autores principales: Herlambang, Fitri, Amelia Dwi, Syauqy, Ahmad, Yuwono, Puspasari, Anggelia, Enis, Rina Nofri, Faried, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792221/
https://www.ncbi.nlm.nih.gov/pubmed/33413630
http://dx.doi.org/10.1186/s13104-020-05437-z