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Surface charge modulation of rifampicin-loaded PLA nanoparticles to improve antibiotic delivery in Staphylococcus aureus biofilms

BACKGROUND: After the golden age of antibiotic discovery, bacterial infections still represent a major challenge for public health worldwide. The biofilm mode of growth is mostly responsible for chronic infections that current therapeutics fail to cure and it is well-established that novel strategie...

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Detalles Bibliográficos
Autores principales: Da Costa, David, Exbrayat-Héritier, Chloé, Rambaud, Basile, Megy, Simon, Terreux, Raphaël, Verrier, Bernard, Primard, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792288/
https://www.ncbi.nlm.nih.gov/pubmed/33413448
http://dx.doi.org/10.1186/s12951-020-00760-w