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Associations of Alzheimer’s disease risk variants with gene expression, amyloidosis, tauopathy, and neurodegeneration

BACKGROUND: Genome-wide association studies have identified more than 30 Alzheimer’s disease (AD) risk genes, although the detailed mechanism through which all these genes are associated with AD pathogenesis remains unknown. We comprehensively evaluate the roles of the variants in top 30 non-APOE AD...

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Detalles Bibliográficos
Autores principales: Tan, Meng-Shan, Yang, Yu-Xiang, Xu, Wei, Wang, Hui-Fu, Tan, Lin, Zuo, Chuan-Tao, Dong, Qiang, Tan, Lan, Suckling, John, Yu, Jin-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792349/
https://www.ncbi.nlm.nih.gov/pubmed/33419465
http://dx.doi.org/10.1186/s13195-020-00755-7