Human umbilical cord mesenchymal stem cell-derived exosomal miR-27b attenuates subretinal fibrosis via suppressing epithelial–mesenchymal transition by targeting HOXC6

BACKGROUND AND AIM: Subretinal fibrosis resulting from neovascular age-related macular degeneration (nAMD) is one of the major causes of serious and irreversible vision loss worldwide, and no definite and effective treatment exists currently. Retinal pigmented epithelium (RPE) cells are crucial in m...

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Detalles Bibliográficos
Autores principales: Li, Dongli, Zhang, Junxiu, Liu, Zijia, Gong, Yuanyuan, Zheng, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792361/
https://www.ncbi.nlm.nih.gov/pubmed/33413548
http://dx.doi.org/10.1186/s13287-020-02064-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792361/
https://www.ncbi.nlm.nih.gov/pubmed/33413548
http://dx.doi.org/10.1186/s13287-020-02064-0

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