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Defining the Cardiac Fibroblast Secretome in a Fibrotic Microenvironment

BACKGROUND: Cardiac fibroblasts (CFs) have the ability to sense stiffness changes and respond to biochemical cues to modulate their states as either quiescent or activated myofibroblasts. Given the potential for secretion of bioactive molecules to modulate the cardiac microenvironment, we sought to...

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Detalles Bibliográficos
Autores principales: Ceccato, Tova L., Starbuck, Rachel B., Hall, Jessica K., Walker, Cierra J., Brown, Tobin E., Killgore, Jason P., Anseth, Kristi S., Leinwand, Leslie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792426/
https://www.ncbi.nlm.nih.gov/pubmed/32924724
http://dx.doi.org/10.1161/JAHA.120.017025