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Inhibitory effect of isomorellin on cholangiocarcinoma cells via suppression of NF-κB translocation, the phosphorylated p38 MAPK pathway and MMP-2 and uPA expression

Evidence indicates that most cancer deaths are caused by tumor invasion and metastasis. Cholangiocarcinoma (CCA) is a tumor of the bile duct epithelium characterized by slow growth, rapid metastasis and poor prognosis. Caged xanthones are extracted from gamboge, a dry resin exuded by Garcinia hanbur...

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Detalles Bibliográficos
Autores principales: Hahnvajanawong, Chariya, Sahakulboonyarak, Thitiporn, Boonmars, Thidarut, Reutrakul, Vichai, Kerdsin, Anusak, Boueroy, Parichart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792505/
https://www.ncbi.nlm.nih.gov/pubmed/33456518
http://dx.doi.org/10.3892/etm.2020.9583