Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families

Background: The muscarinic receptor antagonist trospium chloride (TCl) is used for pharmacotherapy of the overactive bladder syndrome. TCl is a hydrophilic positively charged drug. Therefore, it has low permeability through biomembranes and requires drug transporters for distribution and excretion....

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Detalles Bibliográficos
Autores principales: Gorecki, Matthias, Müller, Simon F., Leidolf, Regina, Geyer, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792585/
https://www.ncbi.nlm.nih.gov/pubmed/33375004
http://dx.doi.org/10.3390/ijms22010022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792585/
https://www.ncbi.nlm.nih.gov/pubmed/33375004
http://dx.doi.org/10.3390/ijms22010022

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