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Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families
Background: The muscarinic receptor antagonist trospium chloride (TCl) is used for pharmacotherapy of the overactive bladder syndrome. TCl is a hydrophilic positively charged drug. Therefore, it has low permeability through biomembranes and requires drug transporters for distribution and excretion....
Autores principales: | Gorecki, Matthias, Müller, Simon F., Leidolf, Regina, Geyer, Joachim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792585/ https://www.ncbi.nlm.nih.gov/pubmed/33375004 http://dx.doi.org/10.3390/ijms22010022 |
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