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Lack of Cannabinoid Receptor Type-1 Leads to Enhanced Age-Related Neuronal Loss in the Locus Coeruleus

Our laboratory and others have previously shown that cannabinoid receptor type-1 (CB1r) activity is neuroprotective and a modulator of brain ageing; a genetic disruption of CB1r signaling accelerates brain ageing, whereas the pharmacological stimulation of CB1r activity had the opposite effect. In t...

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Detalles Bibliográficos
Autores principales: Gargano, Alessandra, Beins, Eva, Zimmer, Andreas, Bilkei-Gorzo, Andras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792602/
https://www.ncbi.nlm.nih.gov/pubmed/33374940
http://dx.doi.org/10.3390/ijms22010005