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Cholinergic stimulation improves electrophysiological rate adaptation during pressure overload-induced heart failure in rats

Left ventricular (LV) electrical maladaptation to increased heart rate in failing myocardium contributes to morbidity and mortality. Recently, cardiac cholinergic neuron activation reduced loss of contractile function resulting from chronic transverse-ascending aortic constriction (TAC) in rats. We...

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Detalles Bibliográficos
Autores principales: Zasadny, Frederick M., Dyavanapalli, Jhansi, Dowling, N. Maritza, Mendelowitz, David, Kay, Matthew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792708/
https://www.ncbi.nlm.nih.gov/pubmed/33006920
http://dx.doi.org/10.1152/ajpheart.00293.2020