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Amino Acid Transporters Are a Vital Focal Point in the Control of mTORC1 Signaling and Cancer
The mechanistic target of rapamycin complex 1 (mTORC1) integrates signals from growth factors and nutrients to control biosynthetic processes, including protein, lipid, and nucleic acid synthesis. Dysregulation in the mTORC1 network underlies a wide array of pathological states, including metabolic...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792758/ https://www.ncbi.nlm.nih.gov/pubmed/33375025 http://dx.doi.org/10.3390/ijms22010023 |