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Amino Acid Transporters Are a Vital Focal Point in the Control of mTORC1 Signaling and Cancer

The mechanistic target of rapamycin complex 1 (mTORC1) integrates signals from growth factors and nutrients to control biosynthetic processes, including protein, lipid, and nucleic acid synthesis. Dysregulation in the mTORC1 network underlies a wide array of pathological states, including metabolic...

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Detalles Bibliográficos
Autores principales: Cormerais, Yann, Vučetić, Milica, Parks, Scott K., Pouyssegur, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792758/
https://www.ncbi.nlm.nih.gov/pubmed/33375025
http://dx.doi.org/10.3390/ijms22010023