ANP and BNP Exert Anti-Inflammatory Action via NPR-1/cGMP Axis by Interfering with Canonical, Non-Canonical, and Alternative Routes of Inflammasome Activation in Human THP1 Cells

Dysregulated inflammasome activation and interleukin (IL)-1β production are associated with several inflammatory disorders. Three different routes can lead to inflammasome activation: a canonical two-step, a non-canonical Caspase-4/5- and Gasdermin D-dependent, and an alternative Caspase-8-mediated...

Descripción completa

Detalles Bibliográficos
Autores principales: Mezzasoma, Letizia, Talesa, Vincenzo Nicola, Romani, Rita, Bellezza, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792787/
https://www.ncbi.nlm.nih.gov/pubmed/33375031
http://dx.doi.org/10.3390/ijms22010024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792787/
https://www.ncbi.nlm.nih.gov/pubmed/33375031
http://dx.doi.org/10.3390/ijms22010024

Ejemplares similares