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Development of Second Generation Activity-Based Chemical Probes for Sirtuins
NAD(+) (nicotinamide adenine dinucleotide)-dependent protein deacylases, namely, the sirtuins, are important cell adaptor proteins that alter cell physiology in response to low calorie conditions. They are thought to mediate the beneficial effects of calorie restriction to extend longevity and impro...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792806/ https://www.ncbi.nlm.nih.gov/pubmed/33375102 http://dx.doi.org/10.3390/molecules26010011 |