The cGMP-Dependent Protein Kinase 2 Contributes to Cone Photoreceptor Degeneration in the Cnga3-Deficient Mouse Model of Achromatopsia

Mutations in the CNGA3 gene, which encodes the A subunit of the cyclic guanosine monophosphate (cGMP)-gated cation channel in cone photoreceptor outer segments, cause total colour blindness, also referred to as achromatopsia. Cones lacking this channel protein are non-functional, accumulate high lev...

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Detalles Bibliográficos
Autores principales: Koch, Mirja, Scheel, Constanze, Ma, Hongwei, Yang, Fan, Stadlmeier, Michael, Glück, Andrea F., Murenu, Elisa, Traube, Franziska R., Carell, Thomas, Biel, Martin, Ding, Xi-Qin, Michalakis, Stylianos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793084/
https://www.ncbi.nlm.nih.gov/pubmed/33374621
http://dx.doi.org/10.3390/ijms22010052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793084/
https://www.ncbi.nlm.nih.gov/pubmed/33374621
http://dx.doi.org/10.3390/ijms22010052

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