Discovery of Novel Symmetrical 1,4-Dihydropyridines as Inhibitors of Multidrug-Resistant Protein (MRP4) Efflux Pump for Anticancer Therapy

Despite the development of targeted therapies in cancer, the problem of multidrug resistance (MDR) is still unsolved. Most patients with metastatic cancer die from MDR. Transmembrane efflux pumps as the main cause of MDR have been addressed by developed inhibitors, but early inhibitors of the most p...

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Detalles Bibliográficos
Autores principales: Döring, Henry, Kreutzer, David, Ritter, Christoph, Hilgeroth, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793087/
https://www.ncbi.nlm.nih.gov/pubmed/33375210
http://dx.doi.org/10.3390/molecules26010018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793087/
https://www.ncbi.nlm.nih.gov/pubmed/33375210
http://dx.doi.org/10.3390/molecules26010018

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