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Signatures of host–pathogen evolutionary conflict reveal MISTR—A conserved MItochondrial STress Response network

Host–pathogen conflicts leave genetic signatures in genes that are critical for host defense functions. Using these “molecular scars” as a guide to discover gene functions, we discovered a vertebrate-specific MItochondrial STress Response (MISTR) circuit. MISTR proteins are associated with electron...

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Detalles Bibliográficos
Autores principales: Sorouri, Mahsa, Chang, Tyron, Jesudhasan, Palmy, Pinkham, Chelsea, Elde, Nels C., Hancks, Dustin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793259/
https://www.ncbi.nlm.nih.gov/pubmed/33370271
http://dx.doi.org/10.1371/journal.pbio.3001045