Dis3L2 regulates cell proliferation and tissue growth through a conserved mechanism

Dis3L2 is a highly conserved 3’-5’ exoribonuclease which is mutated in the human overgrowth disorders Perlman syndrome and Wilms’ tumour of the kidney. Using Drosophila melanogaster as a model system, we have generated a new dis3L2 null mutant together with wild-type and nuclease-dead genetic lines...

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Detalles Bibliográficos
Autores principales: Towler, Benjamin P., Pashler, Amy L., Haime, Hope J., Przybyl, Katarzyna M., Viegas, Sandra C., Matos, Rute G., Morley, Simon J., Arraiano, Cecilia M., Newbury, Sarah F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793271/
https://www.ncbi.nlm.nih.gov/pubmed/33370287
http://dx.doi.org/10.1371/journal.pgen.1009297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793271/
https://www.ncbi.nlm.nih.gov/pubmed/33370287
http://dx.doi.org/10.1371/journal.pgen.1009297

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