Increased prostaglandin-D(2) in male STAT3-deficient hearts shifts cardiac progenitor cells from endothelial to white adipocyte differentiation

Cardiac levels of the signal transducer and activator of transcription factor-3 (STAT3) decline with age, and male but not female mice with a cardiomyocyte-specific STAT3 deficiency conditional knockout (CKO) display premature age-related heart failure associated with reduced cardiac capillary densi...

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Detalles Bibliográficos
Autores principales: Stelling, Elisabeth, Ricke-Hoch, Melanie, Erschow, Sergej, Hoffmann, Steve, Bergmann, Anke Katharina, Heimerl, Maren, Pietzsch, Stefan, Battmer, Karin, Haase, Alexandra, Stapel, Britta, Scherr, Michaela, Balligand, Jean-Luc, Binah, Ofer, Hilfiker-Kleiner, Denise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793290/
https://www.ncbi.nlm.nih.gov/pubmed/33370269
http://dx.doi.org/10.1371/journal.pbio.3000739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793290/
https://www.ncbi.nlm.nih.gov/pubmed/33370269
http://dx.doi.org/10.1371/journal.pbio.3000739

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