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Runx proteins mediate protective immunity against Leishmania donovani infection by promoting CD40 expression on dendritic cells

The level of CD40 expression on dendritic cells (DCs) plays a decisive role in disease protection during Leishmania donovani (LD) infection. However, current understanding of the molecular regulation of CD40 expression remains elusive. Using molecular, cellular and functional approaches, we identifi...

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Detalles Bibliográficos
Autores principales: Akhtar, Md. Naushad, Mishra, Manish, Yadav, Vinod, Yadav, Manisha, Gujar, Ravindra, Lal, Sunaina, Kumar, Raj, Khatri, Neeraj, Sen, Pradip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793297/
https://www.ncbi.nlm.nih.gov/pubmed/33370418
http://dx.doi.org/10.1371/journal.ppat.1009136