Cargando…

Runx proteins mediate protective immunity against Leishmania donovani infection by promoting CD40 expression on dendritic cells

The level of CD40 expression on dendritic cells (DCs) plays a decisive role in disease protection during Leishmania donovani (LD) infection. However, current understanding of the molecular regulation of CD40 expression remains elusive. Using molecular, cellular and functional approaches, we identifi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Akhtar, Md. Naushad, Mishra, Manish, Yadav, Vinod, Yadav, Manisha, Gujar, Ravindra, Lal, Sunaina, Kumar, Raj, Khatri, Neeraj, Sen, Pradip
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793297/ https://www.ncbi.nlm.nih.gov/pubmed/33370418 http://dx.doi.org/10.1371/journal.ppat.1009136

Ejemplares similares

Leishmania donovani Attenuates Dendritic Cell Trafficking to Lymph Nodes by Inhibiting C-Type Lectin Receptor 2 Expression via Transforming Growth Factor-β
por: Yadav, Manisha, et al.
Publicado: (2023)

TIM-3 increases the abundance of type-2 dendritic cells during Leishmania donovani infection by enhancing IL-10 production via STAT3
por: Mishra, Manish, et al.
Publicado: (2023)

Leishmania donovani Impedes Antileishmanial Immunity by Suppressing Dendritic Cells via the TIM-3 Receptor
por: Akhtar, Md. Naushad, et al.
Publicado: (2022)

Leishmania donovani Isolates with Antimony-Resistant but Not -Sensitive Phenotype Inhibit Sodium Antimony Gluconate-Induced Dendritic Cell Activation
por: Haldar, Arun Kumar, et al.
Publicado: (2010)

LEISHMANIA DONOVANI IN THE PERIPHERAL BLOOD
por: Young, Charles W., et al.
Publicado: (1923)

Identification and Characterization of miRNAs in Response to Leishmania donovani Infection: Delineation of Their Roles in Macrophage Dysfunction
por: Tiwari, Neeraj, et al.
Publicado: (2017)

In Vitro Assessment of Antifungal Caspofungin on Leishmania donovani Culture Isolation
por: Bhattarai, Narayan Raj, et al.
Publicado: (2017)

Proteomic analysis of the secretome of Leishmania donovani
por: Silverman, J Maxwell, et al.
Publicado: (2008)

Surface antigens of Leishmania donovani promastigotes
Publicado: (1983)

Vaccine Development Against Leishmania donovani
por: Das, Amrita, et al.
Publicado: (2012)

Leishmania donovani bodies in bone marrow
por: Ali, Natasha, et al.
Publicado: (2014)

Leishmania donovani infection induce differential miRNA expression in CD4+ T cells
por: Kumar, Vinod, et al.
Publicado: (2020)

Corrigendum: Identification and Characterization of miRNAs in Response to Leishmania donovani Infection: Delineation of Their Roles in Macrophage Dysfunction
por: Tiwari, Neeraj, et al.
Publicado: (2017)

Seasonal Variation in the Prevalence of Sand Flies Infected with Leishmania donovani
por: Tiwary, Puja, et al.
Publicado: (2013)

L-Asparaginase of Leishmania donovani: Metabolic target and its role in Amphotericin B resistance
por: Singh, Jasdeep, et al.
Publicado: (2017)

Immunogenicity and Protective Efficacy of T-Cell Epitopes Derived From Potential Th1 Stimulatory Proteins of Leishmania (Leishmania) donovani
por: Joshi, Sumit, et al.
Publicado: (2019)

The identification of kala-azar and the discovery of Leishmania donovani.
por: Gibson, M E
Publicado: (1983)

Leishmania donovani and Cutaneous Leishmaniasis, Sri Lanka
por: Siriwardana, H. V. Yamuna D., et al.
Publicado: (2007)

Leishmania donovani Develops Resistance to Drug Combinations
por: García-Hernández, Raquel, et al.
Publicado: (2012)

Hemophagocytosis in Experimental Visceral Leishmaniasis by Leishmania donovani
por: Morimoto, Ayako, et al.
Publicado: (2016)

On Transient Infections with Leishmania Donovani in Man and Animals
por: Knowles, R., et al.
Publicado: (1924)

Global genome diversity of the Leishmania donovani complex
por: Franssen, Susanne U, et al.
Publicado: (2020)

Immunostimulatory Properties of Dendritic Cells after Leishmania donovani Infection Using an In Vitro Model of Liver Microenvironment
por: Donaghy, Ludovic, et al.
Publicado: (2010)

Histone acetyltransferase HAT4 modulates navigation across G2/M and re-entry into G1 in Leishmania donovani
por: Yadav, Aarti, et al.
Publicado: (2016)

Over-Expression of Cysteine Leucine Rich Protein Is Related to SAG Resistance in Clinical Isolates of Leishmania donovani
por: Das, Sanchita, et al.
Publicado: (2015)

Leishmania donovani infection activates Toll-like receptor 2, 4 expressions and Transforming growth factor-beta mediated apoptosis in renal tissues
por: Kumar, Vinod, et al.
Publicado: (2017)

DNA replication protein Cdc45 directly interacts with PCNA via its PIP box in Leishmania donovani and the Cdc45 PIP box is essential for cell survival
por: Yadav, Aarti, et al.
Publicado: (2020)

Central Asian Rodents as Model Animals for Leishmania major and Leishmania donovani Research
por: Vojtkova, Barbora, et al.
Publicado: (2020)

Bone marrow aspirate showing Leishmania donovani in polymorphs
por: Chandra, Harish, et al.
Publicado: (2013)

Seroepidemiology and molecular diversity of Leishmania donovani complex in Georgia
por: Babuadze, Giorgi, et al.
Publicado: (2016)

Fitness of Leishmania donovani Parasites Resistant to Drug Combinations
por: García-Hernández, Raquel, et al.
Publicado: (2015)

A Silver Method of Staining Leishmania Donovani in the Tissues
por: Basu, Charu Chandra
Publicado: (1927)

A Simple Method of Staining Leishmania Donovani in Tissues
por: De, Monindra Nath
Publicado: (1924)

Cancrum Oris in a Monkey Infected with Leishmania Donovani
por: Smith, R. O. A.
Publicado: (1933)

Cytokines and splenic remodelling during Leishmania donovani infection
por: Montes de Oca, Marcela, et al.
Publicado: (2020)

Candidates for Balancing Selection in Leishmania donovani Complex Parasites
por: Grace, Cooper Alastair, et al.
Publicado: (2021)

Correction: DNA replication protein Cdc45 directly interacts with PCNA via its PIP box in Leishmania donovani and the Cdc45 PIP box is essential for cell survival
por: Yadav, Aarti, et al.
Publicado: (2023)

An outbreak investigation of visceral leishmaniasis among residents of Dharan town, eastern Nepal, evidence for urban transmission of Leishmania donovani
por: Uranw, Surendra, et al.
Publicado: (2013)

Comparative Analysis of Cellular Immune Responses in Treated Leishmania Patients and Hamsters against Recombinant Th1 Stimulatory Proteins of Leishmania donovani
por: Joshi, Sumit, et al.
Publicado: (2016)

Single locus genotyping to track Leishmania donovani in the Indian subcontinent: Application in Nepal
por: Rai, Keshav, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_kphbhhss8ba46kue78cur4sg65